The Emperor Constantine I was effectively the sole ruler of the Roman world between 324 and 337 A.D.; his reign was perhaps one of the most crucial of all the emperors in determining the future course of western civilization. By beginning the process of making Christianity the religious foundation of his realm, he set the religious course for the future of Europe, which remains in place to this very day. Because he replaced Rome with Constantinople as the center of imperial power, he made it clear that the city of Rome was no longer the center of power and he set the stage for the Middle A…