What is the Organ Care System?
The first commercial, portable, warm blood perfusion system that allows a new type of organ transplant.
It is designed to maintain organs in a warm, functioning state outside of the body to optimize their health and allow continuous clinical evaluation.
Historical challenges
Challenge No. 1 - Hemolysis
Novel pulsatile pump, valves, circuit, and cannulae design to reduce shear stress and minimize hemolysis
Challenge No. 2 - Biocompatibility & Inflammation
Biocompatible materials used for all blood contacting surfaces
Leukocyte and platelet depletion
Heparin coating of surface area of the perfusion circuit
Use of TMI solution
Challenge No. 3 - Substrate Depletion
TransMedics’ solution sets designed to supply and maintain steady state of needed substrate to ensure stable metabolic function
Challenge No. 4 - Contamination
Dual barrier chamber design
Access for sampling and antibiotics administration
Challenge No. 5 - Portability
Robust design using lightweight composite materials and custom power and gas sources.…
